Status:
COMPLETED
Genetic Screening and Assisted Oocyte Activation in Couples with Diminished/aberrant Embryonic Development.
Lead Sponsor:
University Hospital, Ghent
Conditions:
Embryo
Embryo Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is an interventional comparative study at the Department of Reproductive Medicine at Ghent University Hospital. Patients with previous embryo developmental problems are eligible for the study. Pa...
Detailed Description
Assisted Oocyte Activation (ICSI-AOA) will be the treatment for these patients to overcome their previous embryo developmental problems. This protocol artificially induces calcium rises in the oocyte,...
Eligibility Criteria
Inclusion
- patients with one or more previous ICSI cycles (UZ Gent) AND
- patients with:
- complete developmental arrest (no transfer), or
- complete developmental delay (no morula/blastocyst on Day 5), or
- significantly reduced blastocyst formation (≤15%)
- willing and able to give informed consent
Exclusion
- patients which went for oocyte or sperm donation
- patients with severe male infertility or low fertilization (\<33%) after ICSI
- cycles requiring surgical sperm recovery procedures
Key Trial Info
Start Date :
January 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 9 2022
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT03354013
Start Date
January 15 2018
End Date
September 9 2022
Last Update
September 19 2024
Active Locations (1)
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1
Ghent University Hospital
Ghent, East-Flandres, Belgium, 9000