Status:

COMPLETED

Positive Node Traced Before Neoadjuvant Chemotherapy (NAC)

Lead Sponsor:

Shengjing Hospital

Conditions:

Breast Cancer

Eligibility:

All Genders

Phase:

NA

Brief Summary

To investigate this regression model by injecting and tracing carbon nanoparticles (CNs) into the fusion node prior to NAC in patients with breast cancer.

Detailed Description

Guided by ultrasound, 0.3 mL of CNs suspension was injected in a fusion node prior to NAC in 110 patients with local advanced breast cancer. Patients underwent breast surgery and total axillary lymph ...

Eligibility Criteria

Inclusion

  • invasive ductal carcinoma diagnosed by biopsy;
  • clinically positive node diagnosed by contrast enhance computer tomography (CECT), the number of strengthened nodes at Level I ≥ 1 with the longest diameter of the strengthened node ≥ 2cm;
  • NAC regimen followed the NCCN guideline;
  • no prior history of breast cancer or other malignancies.

Exclusion

  • the cycle number of neo-adjuvant chemotherapy is equal to or less than 2

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2018

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT03355261

Start Date

July 1 2014

End Date

July 1 2018

Last Update

February 20 2020

Active Locations (3)

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Page 1 of 1 (3 locations)

1

The Second Hospital of Jilin University

Changchun, Jilin, China

2

the First Affiliated Hospital of China Medical University

Shenyang, Liaoning, China, 110001

3

Shengjing Hospital of China Medical University

Shenyang, Liaoning, China, 110004