Status:
COMPLETED
Comparison of Triazolam and Midazolam for Anxiolysis During Dental Treatment in the Pediatric Patient
Lead Sponsor:
University of Pittsburgh
Conditions:
Dental Anxiety
Eligibility:
All Genders
7-17 years
Phase:
NA
Brief Summary
This study will evaluate the perceptions of the effects of two anxiolytic medications commonly used during dental treatment in patients weighing 40 kilograms or more.
Detailed Description
Midazolam and nitrous oxide are commonly used in pediatric patients requiring anxiolysis during dental treatment. Triazolam and nitrous oxide are commonly used in adult patients requiring anxiolysis d...
Eligibility Criteria
Inclusion
- Weigh 40 kilograms or more.
- 2/4 or 3/4 Frankl Behavioral Rating at their evaluation appointment.
- Dental treatment that requires two sedation appointments. Dental treatment that requires sedation includes: fillings, crowns, pulpotomies and/or extractions.
- Between the ages of 7-17 years old.
Exclusion
- Patients taking any of the following medications will be excluded from the study: Atripia, cimetidine, diltiazem, erythromycin, fluconazole, grapefruit juice, isoniazid, itraconazole, ketoconazole, nefazodone, rifampicin, ritonavir, fusidic acid, idelalisisb, methadone, olanzapine, thalidomide and/or troleandomycin.
- Pregnant patients will be excluded.
- Patients that have HIV-1 that is being treated with a protease inhibitor will be excluded.
- Patients with a MTHFR mutation will be excluded.
- Patients with acute narrow angle glaucoma will be excluded.
- Patients that have had a previous adverse, paradoxical or allergic reaction to any benzodiazepines will be excluded from the study.
- Patients unable to swallow medication in tablet form.
- Patients that do not speak English as their primary language.
Key Trial Info
Start Date :
January 26 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 11 2018
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT03360123
Start Date
January 26 2018
End Date
April 11 2018
Last Update
June 19 2018
Active Locations (1)
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1
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, United States, 15224