Status:

COMPLETED

Discontinuation of Antidepressant Medication in Primary Care.

Lead Sponsor:

Radboud University Medical Center

Collaborating Sponsors:

Pro Persona Mental Health Care Foundation

Innovatiefonds Zorgverzekeraars

Conditions:

Antidepressants

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

To investigate the effectiveness of the combination of Supported Protocolized Discontinuation (SPD) and Mindfulness-Based Cognitive Therapy (MBCT) in comparison with SPD alone in successful discontinu...

Detailed Description

Antidepressant use continues to rise, mainly explained by an increase in the proportion of patients receiving long term treatment. Although treatment guidelines recommend discontinuation after sustain...

Eligibility Criteria

Inclusion

  • • Having received prescriptions for antidepressants in primary care for at least the past nine months

Exclusion

  • Current treatment by a psychiatrist
  • Current diagnosis of substance use disorder
  • Non-psychiatric indication for long-term antidepressant usage (i.e. neuropathic pain)
  • Having participated in a mindfulness training (\> 3 sessions) within the last 5 years
  • Inability to perform the assessments due to cognitive or language difficulties
  • Younger than 18 years

Key Trial Info

Start Date :

February 20 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2019

Estimated Enrollment :

119 Patients enrolled

Trial Details

Trial ID

NCT03361514

Start Date

February 20 2017

End Date

August 1 2019

Last Update

February 5 2020

Active Locations (1)

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Radboud University Medical Centre for Mindfulness, Radboud University Nijmegen Medical Centre

Nijmegen, Gelderland, Netherlands, 6500HB