Status:

COMPLETED

Post-extubation High-flow Nasal Oxygen for Preventing Extubation Failure

Lead Sponsor:

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Conditions:

Extubation Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Patients intubated due to acute respiratory failure have a high risk of infectious complications, airway injuries and multiple organic failure, so performing a successful extubation from mechanical ve...

Detailed Description

Intubated patients recovering from primary acute hypoxemic respiratory failure who have passed a spontaneous breathing trial will be included in the study. Following extubation, patients will be rando...

Eligibility Criteria

Inclusion

  • Hypoxemic primary acute respiratory failure
  • Invasive mechanical ventilation for at least 48 hours
  • Successful Spontaneous Breathing Trial

Exclusion

  • Immediate indication for invasive mechanical ventilation
  • Immediate indication for non-invasive mechanical ventilation
  • Self-extubation
  • One or more failed Spontaneous Breathing Trial
  • Chronic respiratory failure
  • Neuromuscular diseases
  • Tracheostomy.
  • Nasal cavity pathology
  • Facial surgery
  • Failure to authorize the informed consent

Key Trial Info

Start Date :

October 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 30 2019

Estimated Enrollment :

127 Patients enrolled

Trial Details

Trial ID

NCT03361683

Start Date

October 1 2017

End Date

July 30 2019

Last Update

August 8 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

National Institute of Medical Science and Nutrition Salvador Zubirán,

México, Mexico, 14080