Status:
TERMINATED
Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide
Lead Sponsor:
Thomas Jefferson University
Conditions:
Nasal Polyps
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Prior studies have suggested that topical furosemide may reduce the recurrence of sinonasal polyposis following sinus surgery. This project aims to further investigate that claim through a blinded ran...
Eligibility Criteria
Inclusion
- Patients with chronic rhinosinusitis and sinonasal polyposis who are candidates for functional endoscopic sinus surgery
Exclusion
- Hypersensitivity to furosemide or sulfonamides
- pregnancy
- history of tinnitus
- history of sensorineural hearing loss
- poorly controlled diabetes
- current diuretic therapy
- known electrolyte disorder
- currently taking aminoglycosides
- BUN and creatinine levels out of the normal range
- history of renal disease
- allergy to sulfonamides
Key Trial Info
Start Date :
December 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 14 2022
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT03362515
Start Date
December 1 2017
End Date
April 14 2022
Last Update
August 30 2023
Active Locations (1)
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1
Thomas Jefferson University Department of Otolaryngology
Philadelphia, Pennsylvania, United States, 19107