Status:

UNKNOWN

Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients

Lead Sponsor:

Peking University People's Hospital

Conditions:

Low Back Pain

Eligibility:

All Genders

20-60 years

Brief Summary

The present study is aimed to assess the LTP-like pain amplification in chronic low back pain patients to explore the central and peripheral effect for pain LTP.

Detailed Description

This study is a cross-sectional study. Two groups, including low back pain group and healthy subjects group will be arranged in this study. 50 subjects will be recruited in each group, The healthy sub...

Eligibility Criteria

Inclusion

  • Chronic low back pain patients
  • Age 21-80 years old.
  • People must have experienced low back pain for at least 3 months and have reported a minimal pain level of 30 (pain threshold) on the 0-100 pain numerical rating scale (NRS) in the last 7 days.

Exclusion

  • Age below 21 or over 80 years old.
  • Patients were excluded if they had taken pain medications on the day of the assessment or if they had serious spinal pathologies, such as fractures, tumors or inflammatory diseases, such as ankylosing spondylitis, nerve root compromise confirmed by clinical neurological tests or severe cardiorespiratory diseases. Those who were pregnant, patients with cancer and those with a cardiac pacemaker were also excluded.
  • Healthy volunteers.
  • Inclusion Criteria:
  • Age 21-80 years old.
  • These participants must not have presented episodes of low back pain for more than 7 days in the last 12 months.

Key Trial Info

Start Date :

March 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2018

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT03362827

Start Date

March 1 2018

End Date

December 31 2018

Last Update

December 5 2017

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