Status:
UNKNOWN
The Study of Neuromuscular Exercise Therapy and Patients Self-management Program in Knee Osteoarthritis
Lead Sponsor:
Peking University People's Hospital
Collaborating Sponsors:
Beijing Jishuitan Hospital
General Hospital of Beijing PLA Military Region
Conditions:
Exercise Therapy
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
Osteoarthritis is the most common chronic disabling disease,the importance of patient's self-management in chronic disease has been paid more and more attention internationally. Currently, the self-ma...
Detailed Description
The study plans to enroll patients above 50 years old who suffered from knee OA, but patients meets any of the exclusion criteria will not be enrolled. 400 patients of knee OA will be randomly divided...
Eligibility Criteria
Inclusion
- \-
- Clinical diagnosis of knee osteoarthritis, Diagnostic criteria is based on the Chinese medical association's 2007 diagnosis and treatment guidelines for osteoarthritis:
- Repeated knee joint pain within 1 month;
- X-ray(weight-bearing or not)shows narrowed joint space,sclerosis and (or) cystic degeneration of subchondral bone, osteophytes of the joints;
- The joint fluid (at least twice) is clear and viscous, WBC\<2000个/ml;
- Age of patients ≥40 yrs;
- Morning stiffness≤3 min;
- Bone friction in the activity; Note：Combine clinical feature, laboratory and X-ray examination,when the patients meet(1)+(2) or (1)+(3)+(5)+(6) or (1)+(4)+(5)+(6)，they can be diagnosis as knee osteoarthritis.
- VAS≥4分; 3.No surgical treatment is planned within 6 months;
Exclusion
- Other types of arthritis, such us RA(rheumatoid arthritis)
- Severe deformity of knee joint;
- Over obesity patients（BMI\>35）;
- Other comorbidities that would severely affect somatic function, such as: cerebral infarction, lumbar disease that meets surgical indications, lower extremity angiopathy;
- Decompensated cardiac dysfunction;
- Severe cardiovascular and cerebrovascular diseases, or the patient is too weak for any kinds of exercise;
- Lack of compliance;
Key Trial Info
Start Date :
April 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2019
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT03363490
Start Date
April 1 2018
End Date
December 31 2019
Last Update
April 6 2018
Active Locations (1)
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1
PekingUPH
Beijing, Beijing Municipality, China