Status:
RECRUITING
A Comparison of Four Different Treatment Regimens of Helicobacter Pylori in Chinese Children
Lead Sponsor:
Ying HUANG
Collaborating Sponsors:
Guangzhou Women and Children's Medical Center
The Children's Hospital of Zhejiang University School of Medicine
Conditions:
Helicobacter Infections
Eligibility:
All Genders
6-18 years
Phase:
NA
Brief Summary
With the resistance of Helicobacter pylori increasing, low and unsatisfactory eradication rate (64%) have been observed with standard triple therapy in European children. Which regimen is appropriate ...
Detailed Description
Eligible children were randomly divided into four groups: standard triple therapy, sequential therapy, bismuth quadruple therapy and concomitant therapy. The course of treatment is 14 days. The primar...
Eligibility Criteria
Inclusion
- children 6-18 years of age who were referred for upper endoscopy and confirmed to have Hp infection
Exclusion
- patients were excluded if they had taken proton pump inhibitors, H2-receptor antagonists or antibiotics in the 4 weeks prior to the study. Patients with known antibiotic allergy,hepatic impairment or kidney failure were also excluded. Patients who received Hp therapy before were also excluded.
Key Trial Info
Start Date :
September 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
1440 Patients enrolled
Trial Details
Trial ID
NCT03365609
Start Date
September 20 2017
End Date
December 31 2025
Last Update
February 28 2025
Active Locations (1)
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1
Children's hospital of Fudan university
Shanghai, Shanghai Municipality, China, 201102