Status:

RECRUITING

Sentinel Node Mapping in High Risk Endometrial Cancer

Lead Sponsor:

AC Camargo Cancer Center

Conditions:

Endometrial Cancer

Lymph Node Metastases

Eligibility:

FEMALE

18-75 years

Phase:

NA

Brief Summary

This study will evaluate the role of systematic lymphadenectomy after sentinel node (SLN) mapping in high risk endometrial cancer (high grade histologies or deep myometrial invasion). The participants...

Detailed Description

Although most patients with endometrial cancer present with early-stage disease, the standard treatment still includes systematic lymph node dissection for staging. Recently, SLN mapping has emerged a...

Eligibility Criteria

Inclusion

  • High grade histologies (endometrioid grade 3, serous, clear cell and carcinosarcoma)
  • Endometrioid grades 1 or 2 with myometrial invasion of ≥50%
  • Endometrioid grades 1 or 2 with cervical invasion
  • Clinically suitable to receive systematic lymphadenectomy
  • Consent statement

Exclusion

  • Previous hysterectomy in other institution
  • Presence of extra-uterine disease (peritoneal, visceral or suspicious lymph node metastasis)
  • Previous pelvic node dissection

Key Trial Info

Start Date :

December 22 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 20 2024

Estimated Enrollment :

178 Patients enrolled

Trial Details

Trial ID

NCT03366051

Start Date

December 22 2017

End Date

December 20 2024

Last Update

July 30 2024

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Hospital Erasto Gaertner

Curitiba, Paraná, Brazil

2

Hospital do Cancer de Barretos

Barretos, São Paulo, Brazil

3

AC Camargo Cancer Center

São Paulo, São Paulo, Brazil, 01509010

4

Albert Einstein Hospital

São Paulo, São Paulo, Brazil