Status:

COMPLETED

Longitudinal Interaction Between APOA5 -1131T>C and Overweight Accelerates Arterial Stiffness

Lead Sponsor:

Yonsei University

Conditions:

Overweight and Obesity

Eligibility:

All Genders

30-65 years

Brief Summary

The aim of this study is to evaluate whether the longitudinal interaction between APOA5 -1131C variants and overweight could accelerate age-related increases in arterial stiffness and circulating trig...

Eligibility Criteria

Inclusion

  • Nondiabetic (fasting serum glucose concentration \< 126 mg/dL)
  • Nonobese (BMI ≥ 25 kg/m2)

Exclusion

  • Current and/or past history of cardiovascular disease
  • Diabetes mellitus (fasting glucose levels ≥126 mg/dL)
  • Abnormal liver or renal function
  • Thyroid or pituitary disease
  • Pregnancy or lactation
  • Regular use of any medication

Key Trial Info

Start Date :

January 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2013

Estimated Enrollment :

503 Patients enrolled

Trial Details

Trial ID

NCT03367598

Start Date

January 1 2008

End Date

December 31 2013

Last Update

December 8 2017

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