Status:

COMPLETED

Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation

Lead Sponsor:

5 Santé

Conditions:

Physiology

Eligibility:

All Genders

45-75 years

Phase:

NA

Brief Summary

Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the in...

Detailed Description

Chronic obstructive pulmonary disease (COPD) patients exhibit not only respiratory symptoms but also a peripheral muscular weakness. This weakness is characterized by a loss in strength, harmful for t...

Eligibility Criteria

Inclusion

  • Health insurance
  • Patients : COPD Gold II-IV
  • Patients : No rehabilitation since at least 1 yrs
  • Control : sedentary (\< 9 Voorips)

Exclusion

  • Pregnant women
  • Seizures
  • Unable to give written consent
  • Metalic object above shoulders
  • Dermatological issue concerning surface electrodes
  • Drugs influencing central nervous system
  • Caffeine consumption \> 4 coffee / day
  • Neurological disorders
  • Patients : recent exacerbation (\< 4 weeks)

Key Trial Info

Start Date :

June 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2018

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT03368703

Start Date

June 1 2017

End Date

June 30 2018

Last Update

January 13 2020

Active Locations (1)

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Cliniques du Souffle

Lodève, Herault, France, 34700