Status:
UNKNOWN
Diet Management on Hepatic Encephalopathy of Patients With Variceal Bleeding After Intrahepatic Portosystemic Shunt Creation
Lead Sponsor:
Li Yang
Collaborating Sponsors:
West China Hospital
Conditions:
Hepatic Encephalopathy
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Hepatic encephalopathy is a severe complication of transjugular intrahepatic portosystemic shunt (TIPS) treatment in patients with cirrhosis and variceal bleeding. This study is specially designed to ...
Detailed Description
Hepatic encephalopathy (HE) is a severe complication of TIPS treatment in patients with cirrhosis and variceal bleeding. The overall incidence of post-TIPS encephalopathy ranges between 10% and 50%, a...
Eligibility Criteria
Inclusion
- patients with decompensated liver cirrhosis regardless of the etiology
- acute variceal bleeding or with history of variceal bleeding evidenced by endoscopy
- an age between 18 and 75 years old
Exclusion
- a total bilirubin level more than 3mg/dL (51.3mmol/L)
- a creatinine level greater than 3 mg/dL(265umol/L)
- severe dysfunction of heart and respiratory system
- pregnancy
- uncontrolled neoplasm
- active systemic infection
- history of any kind of encephalopathy, mental disease, alcohol dependence, or any other status that influence brain function
- diabetes or any other metabolic diseases
Key Trial Info
Start Date :
October 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2018
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT03372499
Start Date
October 1 2017
End Date
December 1 2018
Last Update
December 13 2017
Active Locations (1)
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1
West China Hospital, Sichuan University
Chengdu, Sichuan, China, +86