Status:
RECRUITING
A Registry Study on Biomarkers of Takayasu's Arteritis (ARSBTA)
Lead Sponsor:
Beijing Institute of Heart, Lung and Blood Vessel Diseases
Collaborating Sponsors:
Shanghai Zhongshan Hospital
Peking University People's Hospital
Conditions:
Takayasu's Arteritis
Eligibility:
All Genders
18-70 years
Brief Summary
Takayasu arteritis is a chronic vasculitis mainly involving the aorta and its main branches such as the brachiocephalic, carotid, subclavian, vertebral, and renal arteries, as well as the coronary and...
Eligibility Criteria
Inclusion
- Retrospective
- Subjects who met the American College of Rheumatology 1990 classification criteria for Takayasu arteritis:
- Age of onset ≤40 years,
- Claudication of upper or lower extremities,
- Decreased pulsation of 1 or both brachial arteries,
- Difference of ≥ 10 mmHg in systolic blood pressure between arms,
- Bruit over subclavian arteries or aorta,
- \*Arteriographic evidence showing a branch of the aorta stenosis or occlusion.
- Meeting more than 3 of 6 criteria suggests the diagnosis of Takayasu arteritis.
- \*Angiography in this study was replaced by vascular magnetic resonance angiography(MRA)or computed tomography angiography(CTA).
Exclusion
- Arteriographic lesions that could be entirely due to atherosclerosis,
- Suffer from other autoimmune diseases (eg, ANCA-associated vasculitis, systemic lupus erythematosus, etc.) besides Takayasu arteritis,
- Cogan's syndrome,
- Behcet's disease,
- Subjects with any serious acute or chronic infection,
- Giant cell arteritis (large vessel vasculitis and at least 50 years old) or other infectious forms of large vessel vasculitis.
- Prospective
- Inclusion Criteria:
- Subjects with initial suspicion of having Takayasu arteritis or patients with Takayasu arteritis need assessment of disease activity were prospectively enrolled.
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT03372980
Start Date
January 1 2016
End Date
December 1 2026
Last Update
April 12 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Beijing Anzhen Hospital
Beijing, Beijing Municipality, China, 100029