Status:

ACTIVE_NOT_RECRUITING

Genetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response

Lead Sponsor:

Hôpital Universitaire Fattouma Bourguiba

Conditions:

Coronary Disease

Eligibility:

All Genders

20+ years

Brief Summary

The pathogenesis of CHD remains poorly known despite much research over the last few decades. Numerous non-genetic variables have been demonstrated to have a significant impact on the risk of CHD. How...

Detailed Description

The pathological basis of CHD is atherosclerosis and its clinical manifestations such as ischemia. The formation of functional collateral circulation around obstructed arteries in ischemic myocardial ...

Eligibility Criteria

Inclusion

  • Patient \>20 years old
  • Established coronary disease

Exclusion

  • Severe hepatic dysfunction
  • Disease or active pathological bleeding (e.g., gastrointestinal (GI) bleeding)
  • Use of glycoprotein IIb/IIIa inhibitors or cilostazol
  • inability to give informed consent.

Key Trial Info

Start Date :

August 12 2015

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2029

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT03373552

Start Date

August 12 2015

End Date

December 31 2029

Last Update

February 27 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Fattouma Bourguiba Hospital

Monastir, Monastir Governorate, Tunisia, 5000