Status:
COMPLETED
Breath Analysis in Children by New Point-of-care Instruments
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Asthma
Cystic Fibrosis
Eligibility:
All Genders
6-16 years
Brief Summary
In this study new hand-held devices for measuring exhaled breath will be tested in children with asthma, CF, and healthy controls. Main objectives will be feasibility and discriminative value of these...
Detailed Description
Rationale: Assessment of volatile organic compounds (VOCs) is a new recently developed non-invasive technique to assess airway inflammation. The non-invasive character makes it highly suitable for use...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Children aged 6 to 16 years
- Healthy group: See exclusion criteria
- Asthma group: Doctor's diagnosed asthma
- Cystic Fibrosis group: A diagnosis of cystic fibrosis, confirmed by a sweat test or genetic analysis
- Exclusion criteria
- Recent course of prednisone or antibiotics (\< 1 month before test)
- Passive smoking
- Other chronic inflammatory disease (e.g. inflammatory bowel disease, rheumatic disease, auto-immune disease)
- Healthy children:
- No current or history of respiratory symptoms
- No current or history of allergic rhinitis
Exclusion
Key Trial Info
Start Date :
March 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT03377686
Start Date
March 1 2016
End Date
December 1 2017
Last Update
December 19 2017
Active Locations (1)
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1
Maastricht University Medical Centre
Maastricht, Netherlands