Status:
UNKNOWN
Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Diabetes
Peripheral Arterial Occlusive Disease
Eligibility:
All Genders
20+ years
Brief Summary
By utilizing Near infrared spectroscopy (NIRS), the local blood flow, tissue oxygenation (StO2), and recovery time of ischemic leg; can be determined. It is reasonable to standardize an easy, simple a...
Detailed Description
Exercise testing by Active Pedal Plantar flexion: The investigators plan to collect 140 cases: 1. Healthy subjects with no apparent atherosclerotic risk \[\< 65 y/o, no diabetic mellitus (DM), no hy...
Eligibility Criteria
Inclusion
- type 1 diabetic patients
- type 2 diabetic patients
Exclusion
- Pregnancy
- Critical limb ischemia (gangrene change)
- A permanent pacemaker implant
- Systolic BP ≥ 200 mmHg or diastolic BP ≥100 mmHg
- Symptomatic orthostatic blood pressure drop ≥ 20 mmHg
- Severe critical aortic stenosis
- Acute medical illness, fever, systemic infection
- Uncontrolled atrial or ventricular dysrhythmias
- Uncontrolled sinus tachycardia≥ 120/min
- Peripheral venous insufficiency, thrombosis or thrombophlebitis
- Those who has factors known to influence the PWV
- The brachial-ankle PWV could not be measured on the right and left sides
- Orthopedic condition (ankle or foot) that cannot perform an active pedal plantar flexion (APP) technique (arthritis, hemiparesis, balance impairment etc.)
Key Trial Info
Start Date :
December 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2019
Estimated Enrollment :
650 Patients enrolled
Trial Details
Trial ID
NCT03378024
Start Date
December 1 2016
End Date
April 30 2019
Last Update
December 19 2017
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