Status:
COMPLETED
Precision High-Intensity Training Through Epigenetics (PHITE)
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
Wright State University
Salk Institute for Biological Studies
Conditions:
Healthy
Eligibility:
All Genders
18-27 years
Phase:
NA
Brief Summary
The PHITE collaborative team, consisting of Tim Broderick, MD (Overall PI), Wright State University (WSU); Marcas Bamman, PhD (Site PI), The University of Alabama at Birmingham (UAB); and Ron Evans, P...
Detailed Description
Overview: The US military relies on physical training to increase and maintain force readiness. In this study, we hypothesize that epigenetic modification is a primary mechanism by which specific phy...
Eligibility Criteria
Inclusion
- Healthy 18-27 year olds who are not in the US armed forces
Exclusion
- History of regular endurance or resistance training in past 12 months
- BMI\>30
- Inability to tolerate intense exercise
- Diabetes
- Uncontrolled hypertension
- Unstable or exercise induced angina pectoris or myocardial ischemia
- Vascular disease
- Neurologic disease
- Musculoskeletal disorder
- Mental health disorder
- Any chronic or infectious disease that would preclude full participation
- Lidocaine allergy
- Pregnancy
Key Trial Info
Start Date :
February 23 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2021
Estimated Enrollment :
239 Patients enrolled
Trial Details
Trial ID
NCT03380923
Start Date
February 23 2017
End Date
July 31 2021
Last Update
October 7 2021
Active Locations (1)
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1
University of Alabama at Birmingham, Center for Exercise Medicine
Birmingham, Alabama, United States, 35205