Status:
UNKNOWN
Research of Intensive Metabolic Intervention Before Pregnancy in PCOS
Lead Sponsor:
RenJi Hospital
Conditions:
PCOS
Impaired Glucose Tolerance
Eligibility:
FEMALE
18-40 years
Phase:
PHASE4
Brief Summary
To investigate whether intensive metabolic intervention of PCOS women before pregnancy can improve pregnancy outcome.Besides, the investigators aim to investigate the best therapy strategy of metaboli...
Detailed Description
To investigate whether intensive metabolic intervention of PCOS women before pregnancy can improve pregnancy outcome.Besides, the investigators aim to investigate the best therapy strategy of metaboli...
Eligibility Criteria
Inclusion
- PCOS women at Childbearing Age
- PCOS: Clinical hyperandrogenism and/or hyperandrogenemia, menstrual dysfunction (oligomenorrhea or amenorrhea) and exclusion of other known disorders. PCOS will be diagnosed using the 2003 Rotterdam criteria.
Exclusion
- Past or present history of a medical disorder or medication known to affect body composition, insulin secretion and sensitivity, or the growth hormone (GH)-insulin-like growth factor 1 (IGF1) axis (eg steroid hormone or thyroid replacement).
- History of current or past pregnancy
- Hormonal contraceptive or metformin use within 3 months of enrollment
- Nonclassical congenital adrenal hyperplasia
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2020
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT03383068
Start Date
January 1 2018
End Date
June 30 2020
Last Update
December 26 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Renji Hospital Department of Endocrinology and Metabolism
Shanghai, Shanghai Municipality, China, 200127