Status:
UNKNOWN
Gut Microbiota Prediction of Metachronous Colorectal Neoplasms
Lead Sponsor:
First Affiliated Hospital of Harbin Medical University
Conditions:
Gut Microbiota
Metachronous Adenoma
Eligibility:
All Genders
35-75 years
Brief Summary
Patients with colorectal cancer are known to be at high risk of developing metachronous adenoma, however, participation in colonoscopy are low. Colonoscopy, the primary modality used all over the word...
Detailed Description
Colorectal cancer(CRC) is one of the most common malignancies in China and in Western countries. Furthermore, those with a history of CRC are at a higher risk for developing metachronous adenomas or C...
Eligibility Criteria
Inclusion
- Requirements of informed consent and assent of participant, parent or legal guardian as applicable
- Patients who underwent exhaustive colorectal cancer surgical resection and accept colonoscopy
- Patients between the age of 35 and 75 years old without considering sex
- Patients with BMI= 18.5-23.9
- Participants can follow the visit plan
Exclusion
- Patients with colorectal cancer with distant metastasis
- Chronic renal diseases and hepatic cirrhosis
- Chronic ischemic heart disease with unstable angina, chronic heart failure at class III or IV and acute myocardial infarction in the last 6 months
- Individuals with a history of Chronic diarrhea
- Individuals with a history of Diabetes mellitus
- Individuals with a history of Hypertension
- Individuals with a history of autoimmune diseases
- Use of antibiotics and probiotics 3 mouth before samples collection
- Individuals with a history of abdominal operation due to any reason
- Individuals with any history of cancer other than colorectal cancer
- Individuals with Inflammatory bowel disease
Key Trial Info
Start Date :
May 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03383159
Start Date
May 1 2016
End Date
September 30 2020
Last Update
June 27 2018
Active Locations (1)
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1
First affiliated hospital of Harbin medical university
Harbin, Heilongjiang, China, 150001