Status:
COMPLETED
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
Lead Sponsor:
University of Malaya
Conditions:
Trauma
Opioid Analgesic Adverse Reaction
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Tramadol is widely used as analgesic in trauma patients. However, it causes side effects, most notably nausea and vomiting. This study aim to determine the role of prophylactic metoclopramide in preve...
Eligibility Criteria
Inclusion
- Patients aged 18 years or older on day of presentation to ETD SGH
- Sustained from traumatic injuries of extremities (Fracture of hand \& wrist, radius, ulna, humerus, femur, tibia, fibula and/or foot \& ankle; laceration wounds of extremities; soft tissue injury)
- Patient who is able to give consent
Exclusion
- Known allergy to metoclopramide
- Concurrently taking medication with anti-emetic effect, including antihistamines, phenothiazines and dopamine antagonists.
- A history of vomiting since time of injury
- Patients who had already received tramadol or metoclopramide in the previous 8 hours prior to arrival at ETD
- Below age of 18 on day of presentation, or patients who could not consent to the study
- Any alteration in level of consciousness
- Hemodynamic instability or primary diagnosis requiring time critical intervention
- Pregnancy or lactation
- History or known case of vertiginous disorder
- Currently undergoing chemotherapy or radiotherapy
Key Trial Info
Start Date :
July 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2017
Estimated Enrollment :
191 Patients enrolled
Trial Details
Trial ID
NCT03383315
Start Date
July 1 2017
End Date
September 30 2017
Last Update
December 26 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sarawak General Hospital
Kuching, Sarawak, Malaysia, 93586