Status:
COMPLETED
Optimization of Contrast Agent Dose in CT With Lean Body Weight
Lead Sponsor:
IRCCS Policlinico S. Donato
Conditions:
Contrast Agent With Lean Body Weight
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study evaluates the different enhancement using a contrast agent dose in computed tomography based on total body weight or based on lean body weight. Half of participants will receive contrast ag...
Detailed Description
Patients will undergo a CT scan of abdomen (multi-phasic) with contrast agent and will be measured: total body weight (TBW), height, lean body weight (LBW) and body mass index (BMI) through formulas k...
Eligibility Criteria
Inclusion
- Patient ≥ 18 years of age;
- Patients who will perform a contrast-enhanced abdominal CT multi-phasic in our institutions;
- Patients able to give informed consent.
Exclusion
- history of chronic underlying liver disease (cirrhosis, fatty infiltration of the liver, or glycogen storage disease);
- history of chronic underlying heart disease (congestive heart failure, prior cardiac valve replacement, restrictive and/or constrictive pericarditis);
- multiple myeloma;
- hypersensitivity to iodine-containing compounds;
- renal insufficiency (serum creatinine level ≤ 1.8 mg/dL \[159.12 µmol/L\]) or patients with renal failure (eGR \<30 ml/min/1.73 m2);
- patients with antecubital vein that, at medical evaluation, cannot sustain the flow rate of CA injection (see below);
- patients carrier of prosthesis or metal bullets, pacemaker or stimulators;
- patients with liver diseases that affect the entire parenchyma;
- fragile patients which, after radiologist evaluation, require lower dose of CA;
- pregnancy;
- general contraindications to CT examination or reasoned decision of the radiologist.
Key Trial Info
Start Date :
December 18 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 25 2019
Estimated Enrollment :
274 Patients enrolled
Trial Details
Trial ID
NCT03384979
Start Date
December 18 2017
End Date
February 25 2019
Last Update
May 6 2019
Active Locations (1)
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1
IRCCS Policlinico San Donato
San Donato Milanese, Milan, Italy, 20097