Status:
COMPLETED
Impact of Vitamin D Supplementation in Patients With Multiple Sclerosis
Lead Sponsor:
University Medical Centre Maribor
Collaborating Sponsors:
Medical Faculty Maribor
Conditions:
Multiple Sclerosis, Relapsing-Remitting
Vitamin D Deficiency
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
Vitamin D is important risk factor for developing multiple sclerosis (MS) and for disease progression. Patients with MS who had lower vitamin D levels were at increased risk for more clinical attacks ...
Detailed Description
Vitamin D is important risk factor for developing multiple sclerosis (MS) and for disease progression. Patients with MS who had lower vitamin D levels were at increased risk for more clinical attacks ...
Eligibility Criteria
Inclusion
- Relapsing remitting MS
- Treatment with immunomodulatory drug
- Age 18-60 years and
- EDSS (Expanded Disability Status Scale) score less than 5.
Exclusion
- Use of vitamin D supplements in the past 3 months
- Pregnancy, planning pregnancy or nursing
- Relapse of disease and corticosteroids use in past month
- Active inflammation at the start of the study (flu, cystitis etc.)
- Renal disease
- Elevated levels of calcium or parathormone
- Hypersensitivity to vitamin D preparations
- Switching of immunomodulatory drug in past 3 months
- Other autoimmune disease
- History of hyperparathyroidism, liver disease, tuberculosis, sarcoidosis or kidney stones
Key Trial Info
Start Date :
December 19 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2018
Estimated Enrollment :
89 Patients enrolled
Trial Details
Trial ID
NCT03385356
Start Date
December 19 2017
End Date
April 30 2018
Last Update
March 20 2019
Active Locations (1)
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1
University Medical Centre Maribor
Maribor, Slovenia, 2000