Status:
COMPLETED
Donation of Post Mortem Tumor Tissues
Lead Sponsor:
Niguarda Hospital
Collaborating Sponsors:
University of Turin, Italy
Fondazione del Piemonte per l'Oncologia
Conditions:
NSCLC Stage IV
CRC
Eligibility:
All Genders
Brief Summary
DONUM is an observational prospective independent protocol for patients with advanced lung cancer, colorectal cancer or cancer of unknown primary, willing to donate their tumor tissue samples post mor...
Detailed Description
Despite the recent technological advancement in genomic and proteomic, the molecular understanding of clonal evolution in solid tumor patients is hampered by intra tumor heterogeneity (ITH), while rem...
Eligibility Criteria
Inclusion
- Adult patients with confirmed metastatic non-small cell lung cancer (NSCLC), colorectal cancer (CRC), CUP (cancer of unknown origin syndrome) with life expectancy less than or equal to 3/4 months;
- Age ≥18;
- Signed informed consent from patient to enter the study and to undergo post-mortem tissue sampling.
Exclusion
- Medical, or psychological conditions that would preclude informed consent;
- History of high-risk infections (e.g. HIV-positive, hepatitis C, tuberculosis and Creutzfeldt-Jacob disease).
Key Trial Info
Start Date :
February 11 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 30 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03385980
Start Date
February 11 2016
End Date
April 30 2022
Last Update
March 22 2023
Active Locations (1)
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1
ASST GOM Niguarda
Milan, Italy, 20162