Status:
UNKNOWN
Clinical Application of Non-invasive Assessment for Staging Liver Steatosis and Liver Fibrosis
Lead Sponsor:
Beijing Friendship Hospital
Conditions:
Nonalcoholic Fatty Liver Disease
Liver Steatosis
Eligibility:
All Genders
18-65 years
Brief Summary
Nowadays, the morbidity of Nonalcoholic fatty liver disease (NAFLD) show ascending trend year by year, which has become an important public health problem in China. As NAFLD can progress to Non-alcoho...
Eligibility Criteria
Inclusion
- Age:18≤,≥65
- Gender:male or female
- NAFLD patient,agree with the paracentesis of liver tissue
- Regular follow-up
- Signing the Informed Consent Form
Exclusion
- Hepatic decompensation：Including cirrhotic complications,such as ascites,hepatic encephalopathy,digestive tract bleeding,hepatorenal syndrome,spontaneous bacterial peritonitis,and HCC.
- Complications of HBV,HCV,HIV.Complications of alcoholic liver disease,autoimmune liver disease,hereditary metabolic liver disease, drug-induced liver disease and other chronic liver disease.
- AFP\>100ng/ml and imaging indicates malignant occupying.Or AFP still\>100ng/ml within 3 months.
- Creatinine was 1.5 times higher than the upper limit of the normal value.
- Combined with other malignant tumors(except those cured).
- Serious diseases of heart, lung, kidney, brain, blood and other important organs with dysfunction.
- severe neurological and psychiatric diseases (such as epilepsy, depression, mania, schizophrenia, etc.)
- Pregnant women and breast-feeding women.
- The researchers consider that it is not suitable for the patients to participate in this study.
Key Trial Info
Start Date :
December 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2018
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT03386890
Start Date
December 1 2015
End Date
December 31 2018
Last Update
December 29 2017
Active Locations (1)
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1
Beijing Friendship Hospital
Beijing, Beijing Municipality, China, 100000