Status:

COMPLETED

Paracetamol and Metamizole With SPI-guided Anaesthesia for VRS

Lead Sponsor:

Medical University of Silesia

Collaborating Sponsors:

Silesian University of Medicine

Conditions:

Vitreoretinal Surgeries

Postoperative Nausea and Vomiting

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

The aim of this randomized trial is to assess the efficacy of preemptive analgesia using paracetamol or metamizole or both of them under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presenc...

Detailed Description

Monitoring depth of anaesthesia using spectral entropy (SE) and quality of neuromuscular block are routine in modern anaesthesia, whereas monitoring of analgesia still requires further studies. Recent...

Eligibility Criteria

Inclusion

  • written consent to participate in the study
  • written consent to undergo general anaesthesia alone or combined with different techniques of pre-emptive analgesia and vitreoretinal surgery

Exclusion

  • history of allergy to local paracetamol or metamizole
  • necessity of administration of vasoactive drugs influencing SPI monitoring
  • pregnancy

Key Trial Info

Start Date :

January 15 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 16 2022

Estimated Enrollment :

165 Patients enrolled

Trial Details

Trial ID

NCT03389243

Start Date

January 15 2018

End Date

December 16 2022

Last Update

December 15 2023

Active Locations (1)

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Medical University of Silesia

Sosnowiec, Silesian Voivodeship, Poland, 41-200