Status:
COMPLETED
The Role of SCUBE-1 in Ischemia-reperfusion Injury
Lead Sponsor:
Diskapi Yildirim Beyazit Education and Research Hospital
Conditions:
Gonarthrosis
Diabetes
Eligibility:
All Genders
18-70 years
Brief Summary
One consequence of tissue damage caused by tourniquet is ischemia-reperfusion injury. Short-term ischemia leads to vasodilatation and reactive hyperemia resulting in post-ischemic reperfusion microcir...
Detailed Description
After being taken to the operation room, the patient will be divided into two groups as group D (diabetic) and group K (control) by standardized anesthesia monitoring with 5-lead electrocardiogram (EC...
Eligibility Criteria
Inclusion
- Diabetes mellitus
- knee replacement surgery
- using a pneumatic tourniquet
Exclusion
- coronary artery disease
- renal disorders
- cognitive disorders
- bleeding diathesis
- who have passed general anesthesia
- anti-inflammatory drugs treatment
- abnormal HbA1c values
Key Trial Info
Start Date :
January 8 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2019
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03389607
Start Date
January 8 2018
End Date
February 1 2019
Last Update
October 9 2019
Active Locations (1)
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1
university of health siences diskapi yildirim beyazit T&R hospital
Ankara, Turkey (Türkiye)