Status:
COMPLETED
Quantification of Proteomes: L-plastin , Lipocalin and Adiponectin in Chronic Periodontitis and Diabetic Subjects
Lead Sponsor:
Meenakshi Ammal Dental College and Hospital
Conditions:
Periodontal Diseases
Eligibility:
MALE
35-60 years
Brief Summary
The quantification of the proteomes : L-plastin, lipocalin and adiponectin was analysed in the subgingival tissue samples of generalized severe chronic periodontitis patients with and without diabetes...
Detailed Description
The quantification of the proteomes : L-plastin, lipocalin and adiponectin was analysed in the subgingival tissue samples of generalized severe chronic periodontitis patients with and without diabetes...
Eligibility Criteria
Inclusion
- Patients willing to participate in the study.
- Male patients within the age group 35 to 60 years.
- Patients having ≥ 10 natural teeth.
- No history of long term antibiotic use in the past 6 months and no history of diabetes mellitus.
- For Group I:
- • Generalized severe chronic periodontitis subjects (30% or more sites with clinical attachment loss (CAL) ≥ 5mm) without type II diabetes mellitus.
- For Group II:
- • Generalized severe chronic periodontitis subjects (30% or more sites with clinical attachment loss (CAL) ≥ 5mm) diagnosed with type II diabetes mellitus (HbA1C levels ≥7%) for the past 5 years and is under oral medication.
Exclusion
- Patients with systemic conditions, such as cardiovascular and respiratory diseases, HIV infection, immunosuppressive patients and patients under chemotherapy.
- Smokers and other behavioral factors which may influence the study.
- Patients who had undergone periodontal therapy within the previous 6 months.
- Female patients (due to hormonal changes and pregnancy which may alter the oral flora).
- \-
Key Trial Info
Start Date :
October 20 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03391349
Start Date
October 20 2016
End Date
December 1 2017
Last Update
January 5 2018
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