Status:
COMPLETED
Ketamine, Lidocaine and Combination for Postoperative Analgesia in Open Liver Resection
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions:
Hepatectomy
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Lidocaine and ketamine both are being used for perioperative analgesia. Perioperative lidocaine infusion has been shown to reduce postoperative pain and opioid consumption. Perioperative low dose Keta...
Detailed Description
All study participants were monitored according to American Society of Anesthesiologists guidelines. All received intrathecal morphine (300 to 400 mcg) at L3-4 interspace via 25 G Whitacre needle. Par...
Eligibility Criteria
Inclusion
- ASA physical status 2-4
- Elective major liver resection
- Signed informed consent
Exclusion
- ICU admission after surgery
- tracheal extubation not planned after surgery
- language barrier
- mental impairment
- severe coagulopathy
- chronic pain or opioid dependance or both
- alcohol/substance abuse
- allergy to the study drugs
- refusal for spinal
- infection at site of spinal
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2017
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT03391427
Start Date
March 1 2011
End Date
December 30 2017
Last Update
July 6 2023
Active Locations (1)
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1
London Health Sciences Center
London, Ontario, Canada, N6A 5A5