Status:

UNKNOWN

FAECAL MICROBIOTA TRANSPLANTATION IN OBESITY

Lead Sponsor:

Joint Authority for Päijät-Häme Social and Health Care

Collaborating Sponsors:

University of Helsinki

Helsinki University Central Hospital

Conditions:

Obesity, Morbid

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

40 patients meeting the criteria for obesity surgery are enrolled. Fecal microbiota transplantation (FMT) will be administered in gastroscopy 6 months before obesity surgery. 20 of the patients will r...

Eligibility Criteria

Inclusion

  • • Candidates for the bariatric surgery
  • BMI ≥ 40 or BMI ≥35 and at least two obesity-related co-morbidities such as type II diabetes (T2DM), hypertension, sleep apnea and other respiratory disorders, non-alcoholic fatty liver disease, osteoarthritis, lipid abnormalities, gastrointestinal disorders, or heart disease.
  • Availability of consecutive fecal samples during one year
  • Compliance to attend gastroscopy and FMT
  • 18-65 years

Exclusion

  • Unable to provide informed consent
  • Pregnancy
  • Type I Diabetes Mellitus
  • Severe renal insufficiency, GFR\<30%
  • Chronic or recurrent bacterial infection needing antimicrobial treatment
  • Large hiatal hernia

Key Trial Info

Start Date :

January 19 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 28 2021

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03391817

Start Date

January 19 2018

End Date

February 28 2021

Last Update

August 15 2019

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Helsinki University Hospital

Helsinki, Finland

2

Päijät-Häme Central Hospital

Lahti, Finland