Status:
WITHDRAWN
Association of Haptoglobin 2-2 With Postoperative Delirium
Lead Sponsor:
Sun Yat-sen University
Conditions:
Postoperative Delirium
Eligibility:
All Genders
45+ years
Brief Summary
Patients with major orthopedic surgery will be recruited. Participants will be monitored for delirium after surgery. Participants' blood will be harvested for the determination of haptoglobin types, l...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists physical status I to III class for major orthopedic surgery (hip or knee replacement or spinal surgery)
- No psychological and psychiatric history and presentation before surgery
- No major organ dysfunction or failure
Exclusion
- Anemia (hemoglobin \< 100 g/l) preoperatively.
- Requires \> 4 units of allogeneic red blood cell transfusion during the surgery
- Using steroids or anti-psychological and anti-psychiatric drugs. A small dose of steroid for postoperative anti-nausea/vomiting is allowed and will not be considered as a indication for exclusion.
- Can not cooperate with the study
- History of bleeding
- BMI \< 18 or \> 30
- History of hemoglobin metabolism disorder
Key Trial Info
Start Date :
December 20 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2019
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03392480
Start Date
December 20 2017
End Date
December 30 2019
Last Update
June 23 2023
Active Locations (8)
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1
Beijing Jishuitan hospital
Beijing, China, 100009
2
Chinese PLA general hospital
Beijing, China, 100853
3
Xinqiao hospital, Army military medical university
Chongqing, China, 400037
4
Daping Hospital, Army Military Medical University
Chongqing, China, 400042