Status:

COMPLETED

Mechanochemical Ablation Compared to Cyanoacrylate Adhesive

Lead Sponsor:

Imperial College London

Collaborating Sponsors:

Singapore General Hospital

Conditions:

Varicose Veins

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will be comparing the treatment of varicose veins using either mechanochemical ablation (MOCA) or cyanoacrylate adhesive (CAE). Patients will be randomised to receiving either MOCA or CAE. ...

Detailed Description

This will be a randomised clinical trial comparing MOCA to CAE. Patients will be randomised into group A (MOCA) or group B (CAE). Only the endovenous ablation part of the procedure will be randomised ...

Eligibility Criteria

Inclusion

  • Adults over 18 years of age
  • Symptomatic GSV or SSV vein reflux \> 0.5 seconds on colour Duplex

Exclusion

  • Current DVT
  • Recurrent varicose veins
  • Arterial disease (ABPI\<0.8)
  • Vein diameter \< 3mm
  • Patient who are unwilling to participate
  • Inability or unwillingness to complete questionnaires
  • Adverse reaction to sclerosant or cyanoacrylate
  • Not been involved in another venous trial for at least 6 months

Key Trial Info

Start Date :

November 6 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2021

Estimated Enrollment :

167 Patients enrolled

Trial Details

Trial ID

NCT03392753

Start Date

November 6 2017

End Date

December 31 2021

Last Update

August 4 2022

Active Locations (1)

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1

Charing Cross Hospital, Imperial College London

London, United Kingdom, W6 8RF