Status:

COMPLETED

Preventive Arterial Wall Phenotype and Low-dose Fluvastatin/Valsartan Combination

Lead Sponsor:

University Medical Centre Ljubljana

Conditions:

Atherosclerosis

Eligibility:

MALE

40-55 years

Phase:

NA

Brief Summary

The study was designed to test whether short-term treatment with a very low-dose combination of fluvastatin and valsartan could induce improvement of endothelial function, arterial stiffness, vascular...

Detailed Description

The largest population that suffers from cardiovascular events are subjects at moderate cardiovascular risk. However, no effective and safe preventive treatment is available for this population. This ...

Eligibility Criteria

Inclusion

  • moderate cardiovascular risk according to Systematic Coronary Risk Estimation (SCORE) risk charts of the European Society of Cardiology
  • males
  • aged between 40 and 55 years

Exclusion

  • diabetes mellitus
  • manifest peripheral artery disease or carotid artery disease
  • acute infection
  • chronic diseases
  • present therapy with fluvastatin and/or valsartan

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2017

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03393377

Start Date

September 1 2014

End Date

June 1 2017

Last Update

January 8 2018

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