Status:
UNKNOWN
Preoperative Pain and POCD in Elderly Patients
Lead Sponsor:
RenJi Hospital
Conditions:
Postoperative Cognitive Dysfunction
Eligibility:
All Genders
65+ years
Brief Summary
The purpose of this study is to investigate whether preoperative pain is the risk factor of POCD in elder patients.
Detailed Description
Postoperative cognitive dysfunction (POCD) occurs mainly in aged patients. The mechanism of POCD is not clear yet and no effective therapy method. In the present study, we conducted a single-center ob...
Eligibility Criteria
Inclusion
- Elder than 65 years old
- Speak Chinese Mandarin
- Those who will undergo major low limb surgery like hemiarthroplasty or total hip arthroplasty with general anesthesia.
- Signed the inform consent
- American Society of Anesthesiologists classification I to II
Exclusion
- Existing cerebral disease, or have a history of neurological and psychiatric disease including Alzheimer Disease, stroke, epilepsy and psychosis
- Existing cognitive impairment as evidenced by Mini-Mental State Examination scores below 24
- Severe hearing or visual impairment
- Unwillingness to comply with the protocol or procedures
- Cannot communicate with Chinese Mandarin
- Serious pulmonary, heart , liver or renal insufficiency patients
- Had anesthesia or surgery within the past 30 days
Key Trial Info
Start Date :
January 10 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03393676
Start Date
January 10 2018
End Date
March 31 2020
Last Update
March 10 2020
Active Locations (2)
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1
Reni Hospital, Shanghai Jiao Tong University, School of Medicine
Shanghai, Shanghai Municipality, China, 200127
2
Shanghai Ren ji Hospital
Shanghai, Shanghai Municipality, China, 200127