Status:
COMPLETED
Myocardial Mass Determination by FFRct and Absolute Coronary Blood Flow
Lead Sponsor:
Catharina Ziekenhuis Eindhoven
Conditions:
Fractional Flow Reserve
Absolute Flow Measurement
Eligibility:
All Genders
18-75 years
Brief Summary
The background for performing the present study is to compare the mass calculations by CT scanning and by invasive absolute blood flow measurements and thereby corroborating both methods.
Detailed Description
Although knowledge about the myocardial mass (in grams) of the different territories belonging to the major coronary arteries, is of clinical importance to estimate risk of coronary interventions (PCI...
Eligibility Criteria
Inclusion
- Presence of multivessel coronary disease with an indication for multivessel FFR and/or PCI or patients with single vessel disease scheduled for FFR/PCI of that single coronary artery
- Availability of a coronary CT scan performed prior to the scheduled invasive investigation. The time difference between the CT scan and the invasive exam should be less than 3 months.
- Focal lesions only
- Normal left ventricular function
- Age \< 75 years
- Note: previous uncomplicated PCI in any of the coronary arteries is permitted
Exclusion
- Inability to give informed consent
- Diffuse coronary disease
- Tortuous or calcified arteries interfering with reliable invasive FFR assessment
- Previous myocardial infarction or ejection fraction less than 60% by echocardiography or ventriculography or less than 50% by nuclear methods
- Atrial fibrillation interfering with high quality coronary CT scanning
- Contra-indications for CT scanning
- Left main stenosis
- Age \> 75 years
- Pregnancy or desired pregnancy in the future
Key Trial Info
Start Date :
February 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03393871
Start Date
February 1 2018
End Date
March 1 2019
Last Update
July 24 2019
Active Locations (1)
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1
Catharina Hospital
Eindhoven, North Brabant, Netherlands, 5623EJ