Status:
COMPLETED
Serum Concentration of lgG in Patient With Acute Coronary Syndrome
Lead Sponsor:
The First Affiliated Hospital of Dalian Medical University
Collaborating Sponsors:
Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian
Conditions:
Acute Coronary Syndrome
Eligibility:
All Genders
18-80 years
Brief Summary
The aim of this study is to investigate the changes in glycopeptides of serum immunoglobulin G in patients with acute myocardial infarction and the relationships between its change and prognosis.
Detailed Description
Immunoglobin G (IgG), a highly abundant glycoprotein in serum, is known to participate in blood immune responses.It has been an increasing interest in the analysis of the abnormal glycosylation of hum...
Eligibility Criteria
Inclusion
- \- diagnosed as STEMI.
- with left ventricular ejection fraction（LVEF）\>=45%
- written informed consents are obtained
- admitted within 24 hours after chest pain attacked
Exclusion
- complicated with rheumatic heart disease, coronary arteritis, hypertrophic cardiomyopathy or dilated cardiomyopathy
- complicated with malignant tumor,the immune system diseases, blood system diseases, recently (within 2 weeks) taking glucocorticoid drugs, the use of immunosuppressive agents and cerebral infarction
- with acute or chronic infection, surgery or trauma in the last month
- secondary hypertension, severe liver dysfunction,severe renal insufficiency
- with abnormal thyroid function or allergy to iodine agent refusal to sign the informed consent
Key Trial Info
Start Date :
January 15 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2019
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03394092
Start Date
January 15 2018
End Date
March 1 2019
Last Update
March 19 2019
Active Locations (1)
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1
The First Affiliated Hospital of Dalian Medical University
Dalian, China, 116011