Status:

COMPLETED

Continuous Positive Airway Pressure as a Potential New Treatment for Cluster Headache

Lead Sponsor:

St. Olavs Hospital

Collaborating Sponsors:

Norwegian University of Science and Technology

Conditions:

Cluster Headache

Chronic Disease

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Cluster headache is also called suicide headache due to excruciating nocturnal attacks. There are few treatment options available. Inhalation of oxygen has shown to abort the attacks. Continuous posi...

Detailed Description

This is a single center study carried out in collaboration between the neurological, neurophysiological and thoracic departments at St. Olavs Hospital in Trondheim. Participants will keep sleep and h...

Eligibility Criteria

Inclusion

  • Fulfils the diagnostic criteria for chronic cluster headache according to ICHD-3 beta 3.1.2.
  • is able to separate cluster headache attacks from other types of headache.
  • agrees to maintain current preventive headache and sleep medication regimens (no change in type, frequency, or dose) during the whole study period.
  • Signed informed consent.

Exclusion

  • disorders with contraindications for use of continuous positive airway pressure (e.g. unable to remove the ventilation mask due to a movement disorders).
  • Nightly cluster headache attacks
  • Pregnancy or planned pregnancy
  • having had a change in type, dosage or dose frequency of preventive headache or sleep medications \< 1 months prior to inclusion.
  • Severe depression or other psychiatric disorder that may interfere with the treatment.
  • Abuse of alcohol or illicit drugs.
  • Other severe chronic pain conditions

Key Trial Info

Start Date :

January 16 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 21 2019

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03397563

Start Date

January 16 2018

End Date

August 21 2019

Last Update

March 31 2020

Active Locations (1)

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St Olavs Hospital

Trondheim, Norway