Status:
UNKNOWN
IVC Variation After VT Challenge to Predict Fluid Responsiveness
Lead Sponsor:
Shanghai Zhongshan Hospital
Conditions:
Cardiac Surgery
Fluid Challenge
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of the study was to evaluate the efficacy of using the respiratory variation in inferior vena cava diameters as an index of fluid responsiveness after tidal volume challenge in mechanicall...
Detailed Description
The "tidal volume challenge" is a novel test to predict fluid responsiveness in patents in shock, ventilated using low tidal volume without spontaneous breathing activity. The test involves transientl...
Eligibility Criteria
Inclusion
- acute circulatory failure (low blood pressure or urine output, tachycardia, or mottling)
- clinical signs of organ hypoperfusion (renal dysfunction or hyperlactatemia)
Exclusion
- a contraindication to elevation of tidal volume
- evidence of cardiac arrhythmia
- left ventricular ejection fraction less than 50%
- echocardiographic examination that showed the existence of severe tricuspid or mitral regurgitation or right heart dysfunction
- intracardiac shunt
- pulmonary hypertension
- severe chronic obstructive pulmonary disease
- a contraindication to the passive leg raising (PLR) test
- air leakage through chest drains
- abdominal compartment syndrome
- portal hypertension
- pregnancy
- inability to perform ultrasonography
Key Trial Info
Start Date :
February 3 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2019
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03397784
Start Date
February 3 2018
End Date
December 31 2019
Last Update
February 5 2018
Active Locations (1)
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1
Zhongshan Hospital, Fudan University
Shanghai, China, 200032