Status:

COMPLETED

Comparison of BPAP ST/T and BPAP ST / T Mode With AVAPS for Hypercapnic Respiratory Failure in ED

Lead Sponsor:

Dokuz Eylul University

Conditions:

Hypercapnic Respiratory Failure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of the present study; To compare the effects of respiratory support options available for NIMV at the emergency department; i.e. AVAPS and ST/T modes, on the patient's pCO2 values, additional ...

Detailed Description

Non-invasive positive pressure ventilation (NIMV) is a life-saving procedure for patients with hypoxic and/or hypercapnic respiratory failure. AVAPS (average volume assured pressure support) is a noni...

Eligibility Criteria

Inclusion

  • PaCO2 \> 45mmHg and any of the following
  • SaO2 \<90% on air
  • SaO2 \<93% on \>6 Litres O2/min
  • Inability to speak in sentences due to respiratory distress
  • Respiratory rate \> 24/min
  • Altered mental status
  • The use of accessory muscles of respiration

Exclusion

  • Respiratory arrest or unstable cardiorespiratory status
  • Suspected Pneumothorax
  • Urgent need for intubation
  • Systolic blood pressure \< 90 mmHg
  • Inability to protect airway
  • Facial deformity
  • Facial, esophageal, or gastric surgery history
  • All trauma patients
  • Acute myocardial infarction
  • Severe arrythmias
  • Refractory nausea and vomiting

Key Trial Info

Start Date :

October 20 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2017

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT03398239

Start Date

October 20 2016

End Date

August 1 2017

Last Update

January 12 2018

Active Locations (1)

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Dokuz Eylul University Hospital

Izmir, Turkey (Türkiye), 35340