Status:
COMPLETED
Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Lead Sponsor:
Damascus University
Conditions:
Malocclusion, Angle Class II, Division 1
Eligibility:
All Genders
15-27 years
Phase:
NA
Brief Summary
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned t...
Detailed Description
Extraction is a procedure that is currently performed in orthodontics, either in the context of early treatment or for adolescents with severe crowding or protrusion/overjet. The consequences of this ...
Eligibility Criteria
Inclusion
- Adult healthy patients, Male and female, Age range: 15-27 years.
- Class II Division 1 malocclusion:
- Mild / moderate skeletal Class II (ANB ≤7)
- Overjet ≤10
- Normal or excessive facial height (Clinically and then cephalometry assessed using these angles : SN-MP , MM , Y axis)
- Mild to moderate crowding ≤ 4
- permanent occlusion.
- Exist all the upper teeth (except third molars).
- Good oral and periodontal health:
- Probing depth \< 4 mm
- No radiographic evidence of bone loss.
- Gingival index ≤ 1
- Plaque index ≤ 1
Exclusion
- Medical problems that affect tooth movement (corticosteroid, NSAIDs, …)
- patients have anti indication for oral surgery ( medical - social - psycho)
- Presence of primary teeth in the maxillary arch
- Missing permanent maxillary teeth (except third molars).
- Poor oral hygiene or Current periodontal disease:
- Probing depth ≥ 4 mm
- radiographic evidence of bone loss
- Gingival index \> 1
- Plaque index \> 1
- Patient had previous orthodontic treatment
- Craniofacial anomalies (cleft lip and palate patients)
- Smokers
- coagulation disorders and patients treated with anticoagulants.
- patients with immunodeficiency disorders
Key Trial Info
Start Date :
August 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 10 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03399760
Start Date
August 20 2017
End Date
July 10 2019
Last Update
July 18 2019
Active Locations (1)
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1
Damascus University
Damascus, Syria, 00963