Status:
COMPLETED
Effect of Probiotic Consumption on Chronic Kidney Disease
Lead Sponsor:
Centro Universitário Univates
Conditions:
Chronic Kidney Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Recent studies have demonstrated that the balance of intestinal microbiota is affected in chronic kidney disease (CKD), leading to a condition known as intestinal dysbiosis. These changes were associa...
Detailed Description
The assessment will include clinical and nutritional parameters, estimated glomerular filtration rate, proteinuria, serum lipids, inflammatory factors, and bowel habits. The study protocol includes th...
Eligibility Criteria
Inclusion
- Patients with chronic kidney disease stage 3, 4 and 5;
- Stable renal function;
- Proteinuria greater than or equal to 500 mg;
- Patients who agree to participate.
Exclusion
- Patients on renal replacement therapy or kidney transplant;
- Patients with prior renal transplant;
- Patients with acute clinical events;
- Patients using antibiotics or any other medications that can alter the intestinal microbiota as corticosteroids and immunosuppressants in the last three months;
- Patients with active infection;
- Patients with inflammatory bowel diseases or malabsorption;
- Acute or chronic diarrhea;
- Patients with previous intestinal surgery;
- Pregnants.
Key Trial Info
Start Date :
July 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2017
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03400228
Start Date
July 1 2015
End Date
December 31 2017
Last Update
January 17 2018
Active Locations (1)
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1
Thaís Rodrigues Moreira
Porto Alegre, Rio Grande do Sul, Brazil, 90035-903