Status:
COMPLETED
Enteral Nutrition and Vasoactive Drugs
Lead Sponsor:
Hospital Severo Ochoa
Collaborating Sponsors:
Hospital Universitario 12 de Octubre
Conditions:
Enteral Nutrition
Vasopressor Agents
Eligibility:
All Genders
18+ years
Brief Summary
Enteral nutrition in critically ill patients undergoing vasoactive support due to hemodynamic instability is controversial. Hypothesis: enteral nutrition delivered in such patients can be feasible and...
Detailed Description
Nutrition support in critically ill patients undergoing vasoactive support due to hemodynamic instability is controversial and challenging. However, if it is delivered according to an enteral nutritio...
Eligibility Criteria
Inclusion
- Authorization to participate in the study by informed consent.
- Dependence of vasoactive drugs and/or mechanical circulatory support to at least 48 hours from Intensive Care Unit admission.
- Invasive mechanical ventilation time of at least 48 hours.
- Expected survival greater than 72 hours.
- ICU Stay greater than or equal to 72 hours.
Exclusion
- Refusal to participate in the study.
- Refractory shock, defined as the progressive elevation of the dose of vasoactive drugs and / or markers of tissue hypoperfusion, or mean arterial pressure ≤ 60 mm Hg despite the therapeutic maneuvers.
- History of significant abdominal vascular disease (ischemic colitis, chronic mesenteric ischemia, aortic aneurysm abdominal, aortic dissection with involvement of mesenteric vessels, etc).
- Absolute contraindication for the onset of enteral nutrition (active gastrointestinal hemorrhage, intestinal obstruction, etc.) or patients with a non-functional gastrointestinal tract.
Key Trial Info
Start Date :
January 15 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03401632
Start Date
January 15 2017
End Date
June 30 2020
Last Update
July 29 2020
Active Locations (23)
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1
Hospital Regional Universitario de Málaga
Málaga, Andalusia, Spain, 29010
2
Hospital de San Jorge
Huesca, Aragon, Spain, 22004
3
Hospital de Barbastro
Huesca, Aragon, Spain, 22300
4
Hospital Universitario Miguel Servet
Zaragoza, Aragon, Spain, 50009