Status:
UNKNOWN
Sedation Protocols and Skeletal Muscle Metabolism in Mechanical Ventilated Patients
Lead Sponsor:
Chinese Medical Association
Conditions:
Hypercatabolism
Sedative, Hypnotic, or Anxiolytic Use Disorders
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
To investigate the effects of different sedation protocols on skeletal muscle metabolism in mechanical ventilated patients in ICU. Mechanical ventilated patients who are anticipated to stay in ICU for...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- mechanical ventilated for more than 48h
- 18-80 years
- stay in ICU for more than 5 days
- Exclusion Criteria
- already participated in other clinical trials
- pregnancy or lactation
- lower limb amputation
- primary neuro-muscular disease
- disseminated tumor or accepted special therapy
- alcohol abuse
- severe liver dysfunction(Child-Push C)
- unstable angina/acute myocardial infarction
- heart rates\<50bpm
- all kinds dialysis
- severe burn
- epidural anesthesia
- severe neurological disease（acute stroke, uncontrollable epilepsy, severe dementia, etc）
Exclusion
Key Trial Info
Start Date :
December 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2019
Estimated Enrollment :
360 Patients enrolled
Trial Details
Trial ID
NCT03402113
Start Date
December 20 2017
End Date
January 31 2019
Last Update
March 29 2018
Active Locations (1)
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1
The Affliated Drum Tower Hospital, Medical School of Nanjing University
Nanjing, Jiangsu, China, 210008