Status:
COMPLETED
Red Blood Cell ATP Release and Vascular Function in Humans
Lead Sponsor:
Colorado State University
Conditions:
Cardiovascular Diseases
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
Brief Summary
Previous work demonstrates that the red blood cells of older adults do not release a potent vasodilator (ATP) as well as the red blood cells of younger adults. The investigators are targeting a pathwa...
Detailed Description
Participants will initiate contact with the investigators by responding to flyers placed in the community either by phone or email. The first correspondence (phone or email) will provide a brief descr...
Eligibility Criteria
Inclusion
- Healthy
- Sedentary to moderately active
- 18 to 30 years old for young subjects
- 60 to 80 years old for older subjects
Exclusion
- Obesity (BMI ≥ 30 kg/m\^2)
- Cardiovascular disease
- Metabolic disease
- Use of medications that can influence cardiovascular function
- Blood pressure greater than or equal to 140/90
- Smoker
- Use of hormone replacement therapy
Key Trial Info
Start Date :
July 14 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 5 2018
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT03404843
Start Date
July 14 2017
End Date
October 5 2018
Last Update
February 27 2020
Active Locations (1)
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1
Colorado State University, Dept. of Health and Exercise Science
Fort Collins, Colorado, United States, 80523