Status:
UNKNOWN
Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction
Lead Sponsor:
Isfahan University of Medical Sciences
Conditions:
Vitamin D Deficiency
Non-ST Elevation Myocardial Infarction (nSTEMI)
Eligibility:
All Genders
40-65 years
Phase:
PHASE2
Brief Summary
The leading cause of death in the world is due to cardiovascular events, which originate from coronary artery stenosis therefore it affects myocardial blood flow and finally may cause infarction. Athe...
Detailed Description
The leading cause of death in the world is due to cardiovascular events, which originate from coronary artery stenosis therefore it affects myocardial blood flow and finally may cause infarction. ST-S...
Eligibility Criteria
Inclusion
- 30-65 years old patients
- Hypovitaminosis D (serum 25(OH) Vitamin D\< 20 ng/ml)
- Written and informed consent to participate in this project
- Non ST-Segment Elevation Myocardial Infarction: any patients with chest pain or any discomfort and suspected MI who referred to our Heart Center Emergency Room without any ST-Segment Elevation (according to J-point) in 12-lead ECG (according to American Heart Association (AHA) guidelines) plus increasing level of serum cardiac Troponin I
Exclusion
- Normal Vitamin D level
- Body mass index (BMI)\>30 kg/m2
- Do not tend to attend in this study
- Any life-threatening medical condition
- Hyperparathyroidism (parathyroid hormone (PTH)\>upper normal limit according to lab reference range)
- Liver failure (any positive past medical history or Aspartate and Alanine aminotransferase (AST and ALT) 2 times more than normal upper limit)
- Renal Failure (any positive past medical history or Glomerular filtration rate \<60 ml/min/1.73 m2 estimated with MDRD formula of Qx calculate application)
- Any prior history of diagnosed cancer, rheumatologic and immunologic disorders
Key Trial Info
Start Date :
May 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2019
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03405207
Start Date
May 1 2018
End Date
August 1 2019
Last Update
August 20 2018
Active Locations (1)
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1
Cardiovascular Rehabilitation Research Center
Isfahan, Iran