Status:

UNKNOWN

A Study Using MRI To Assess Bladder Motion During Radiotherapy

Lead Sponsor:

The Christie NHS Foundation Trust

Conditions:

Bladder Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The standard non-surgical treatment for muscle invasive bladder cancer is concurrent chemo-radiotherapy. This treatment is associated with long term side effects in around a third of patients with up ...

Detailed Description

Patients will undergo standard treatment during the study with four weeks of external beam radiotherapy (20 fractions). They will be treated with weekly Gemcitabine (100mg/m2) or daily Nicotinamide (6...

Eligibility Criteria

Inclusion

  • Histologically confirmed diagnosis of bladder cancer
  • Treatment with primary curative intent
  • Undergoing external beam radiotherapy (+/-chemotherapy)
  • Age over 18 years

Exclusion

  • Any contraindications to MRI identified after MRI safety screening including completion of an MRI Safety Screening Form
  • Any contraindications to both Hyoscine Butylbromide (Buscopan)
  • Previous cystectomy
  • Unable to tolerate MRI scans
  • Metastatic disease
  • Pregnancy

Key Trial Info

Start Date :

March 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2019

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03409029

Start Date

March 1 2018

End Date

September 1 2019

Last Update

January 30 2018

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A Study Using MRI To Assess Bladder Motion During Radiotherapy | DecenTrialz