Status:
COMPLETED
Supplementation Trial on Arginine With Metabolic Profiling
Lead Sponsor:
Pennington Biomedical Research Center
Collaborating Sponsors:
Jennifer C. Rood
Robbie A. Beyl
Conditions:
Protein
Amino Acid
Eligibility:
MALE
18-39 years
Phase:
NA
Brief Summary
This study will assess effects of an acute dose of the amino acid arginine on metabolism in healthy young men.
Detailed Description
A double - blind randomized, crossover design trial examining arginine vs. placebo beverage treatments will be performed. The primary objective is to determine the effects of arginine assessed by stan...
Eligibility Criteria
Inclusion
- BMI 18.5 - 25 kg/m2.
- Must be physically active (exercise at least 2 days/week).
- Willing to refrain from alcohol and supplements for the duration of the study.
- Willing to refrain from supplement ingestion, nuts, watermelon, and cracklins (fatback) for the 2 weeks prior to the initial treatment diet through the duration of the study.
Exclusion
- HIV or AIDS
- Uncontrolled CVD/arrhythmia
- Type I or type II diabetes
- Pregnancy (or breastfeeding)
- Diagnosed eating disorder
- Non-normal sleeping patterns
- Chronic neurological condition
- Altered metabolism including growth hormone disorders
- Use of nicotine or tobacco products
- Heavy caffeine use (≥ 350 mg caffeine/d)
- Whole blood donation within previous eight weeks
- Protein supplementation
- Protein wasting disease.
- Exclusionary medications include diuretics, beta-blockers, weight loss medications or diet pills, anti-inflammatory drugs (corticosteroid/ anabolic steroid/NSAID), antipsychotic medication or other medication that may affect fluid balance, metabolism, or body weight.
- Prisoners and adults who are unable to consent will be excluded from the study.
- Lastly any other medical, psychiatric, or behavioral factors in the judgement of the Principle Investigator that may interfere with study participation or the ability to follow the protocol.
Key Trial Info
Start Date :
February 8 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 8 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03409380
Start Date
February 8 2018
End Date
July 8 2019
Last Update
September 14 2022
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808