Status:
COMPLETED
Diagnostic Accuracy of FDG PET/CT of Cranial Arteries in GCA
Lead Sponsor:
University of Aarhus
Conditions:
Giant Cell Arteritis
Eligibility:
All Genders
50+ years
Brief Summary
A case-control study to evaluate the diagnostic accuracy of FDG uptake in cranial arteries by FDG PET/CT in the diagnosis of giant cell arteritis.
Detailed Description
Although older studies argue that FDG PET/CT cannot demonstrate inflammation in cranial arteries, e.g. temporal and maxillary arteries, the resolution of modern PET systems may have improved, making a...
Eligibility Criteria
Inclusion
- Cases:
- 1\) age ≥50 years, 2) CRP\>15mg/l or ESR\>40mm/h, 3) either a) cranial symptoms, b) new-onset extremity claudication or c) weight loss \>5 kilograms or fever\>38oC for \>3 weeks and a clinical diagnosis of giant cell arteritis judged by expert rheumatologist.
- Controls:
- age-(+/-3 years) and sex-matched malignant melanoma (MM) patients
- follow-up metastatic-disease-free FDG PET/CT ≥6 months after MM resection
Exclusion
- Previous diagnosis of polymyalgia or giant cell arteritis
- immunosuppresive treatment within last month
Key Trial Info
Start Date :
October 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2017
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT03409913
Start Date
October 1 2014
End Date
December 31 2017
Last Update
January 24 2018
Active Locations (1)
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1
Department of Rheumatology
Aarhus, Denmark, 8000