Status:
COMPLETED
A Feasibility Study to Develop a Protocol for Functional Lacrimal Magnetic Resonance Imaging
Lead Sponsor:
Brighton and Sussex University Hospitals NHS Trust
Conditions:
Lacrimal Duct Obstruction
Lacrimal Stenosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Watering eyes (epiphora) is a very common ophthalmic condition. It is frequently caused by dysfunction of the lacrimal (tear) drainage system which is the 'pipework' that takes tears from the eye to t...
Detailed Description
Tear drainage delay is a common problem that causes a watery eye. This can impair activities of daily living such as reading and driving, can be a huge nuisance requiring continual dabbing with a tiss...
Eligibility Criteria
Inclusion
- Lacrimal drainage disease participants (n=5)
- Symptomatic epiphora (tearing)
- Nasolacrimal drainage dysfunction confirmed by the following characteristics:
- An abnormal delay of tear transit on DSG
- A normal DCG and lacrimal syringing investigation
- Normal eyelid and punctal anatomy
- Controls
- No epiphora
- Normal lacrimal syringing in clinic.
- Exclusion criteria
- Age under 18
- Renal function \<30mL/min/1.73m2
- Contra-indications to MRI e.g. electronic or metal implants, severe claustrophobia
- Known adverse reactions to contrast agents
- Pregnancy
Exclusion
- \-
Key Trial Info
Start Date :
June 13 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2019
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03411889
Start Date
June 13 2018
End Date
March 31 2019
Last Update
March 25 2022
Active Locations (1)
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1
Brighton & Sussex University Hospitals
Brighton, East Sussex, United Kingdom, BN" 5BE