Status:

COMPLETED

Pain in Autism Spectrum Disorder

Lead Sponsor:

Rambam Health Care Campus

Conditions:

High-functioning Autism

Eligibility:

All Genders

18-45 years

Brief Summary

The proposed project will be first performed on individuals with HF-ASD with their expected heterogeneity and healthy control (HC) subjects in order to explore the pain processing and modulation mecha...

Detailed Description

A dysregulation of the balance between excitatory and inhibitory neural activity (i.e. an E/I imbalance) underlies ASD pathology. Neural hyper-responsiveness and impaired top-down modulation represent...

Eligibility Criteria

Inclusion

  • Proficiency in using the Hebrew language;
  • Verbal performance and full scale estimate of 80 and above on the WASI
  • No use of pain medication for the past 24 hours.
  • Inclusion criteria for the ASD group: A diagnosis of HF-ASD based on the ADOS-2

Exclusion

  • 1\) Diagnosis of chronic pain.

Key Trial Info

Start Date :

May 6 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 17 2022

Estimated Enrollment :

183 Patients enrolled

Trial Details

Trial ID

NCT03413241

Start Date

May 6 2018

End Date

February 17 2022

Last Update

April 12 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

The lab of clinical neurophysiology, the faculty of medicine, Technion and Rambam Medical Center

Haifa, Israel